The practical, approachable expert in longevity

Meredith Sweeney, MD, FACS

Fourteen years as a board-certified bariatric surgeon, fixing what metabolic disease does to the body. Now a longevity physician who finds it years earlier and fixes it there. Founder of Sano Longevity in Louisville and Head of Metabolic Optimisation and Longevity at AverCare Global. Her promise to every patient: more years, and more life in those years.

Book Dr. Sweeney to SpeakSee her media and podcasts
Dr. Meredith Sweeney headshot, longevity physician and founder of Sano Longevity, Louisville
  • Featured speaker, LongevityFest, Las Vegas (8,000+ attendees)
  • Fellow, American College of Surgeons
  • Louisville Business First 40 Under Forty
  • 8 podcast appearances since 2025

From the operating room to the longevity clinic

Dr. Meredith Sweeney spent 14 years as a bariatric surgeon in Louisville, Kentucky. Surgery fixes the consequence. She wanted to reach the cause. Today she finds metabolic disease years earlier, through Sano Longevity and her work at AverCare Global.

Credentials
MD, University of Illinois (2006), Fellow of the American College of Surgeons (2015), board certified by the American Board of Surgery (2011)
Current roles
Founder and Chief Medical Officer, Sano Longevity (Louisville, KY); Head of Metabolic Optimisation and Longevity, AverCare Global
Surgical career
Completed general surgery residency, minimally invasive surgery fellowship. She left traditional practice after 14 years in bariatric surgery but still performs general surgery part-time.
Speaking
Featured speaker at LongevityFest, the A4M national conference in Las Vegas, December 2025

Read her full story

Dr. Meredith Sweeney working at her desk, with her Louisville Business First Forty Under 40 award on the shelf behind her

Speaking topics

Dr. Sweeney speaks to medical conferences, corporate wellness programs, and consumer health audiences. Every talk is built on clinical data from her own practice, not a slide deck of someone else's studies.

LongevityFest 2025, Las Vegas, December 12 to 14, where Dr. Meredith Sweeney was a featured speaker

Featured speaker at LongevityFest 2025 in Las Vegas, the largest longevity conference in the United States with more than 8,000 healthcare professionals in attendance. Topic: Changing the Trajectory of Longevity: Using Continuous Glucose Monitoring as a Personalized Medicine Tool to Extend Healthspan.

  • The Science of Longevity: What Actually Moves the Needle

    Which interventions have outcome data behind them, which are marketing, and how to tell the difference.

  • Metabolic Health as the Foundation of Longevity

    Why fasting insulin, visceral fat, and muscle mass predict healthspan better than weight or BMI.

  • Building Metabolic Resilience for a Longer, Healthier Life

    The measurable markers of resilience and the protocols that move them within 90 days.

  • Muscle, Metabolism and the Aging Process

    Muscle as the organ of longevity, and why losing it is the most preventable cause of decline.

  • The Longevity Blueprint: Evidence-Based Strategies for Healthspan

    A practical order of operations for patients and clinicians, from baseline testing to intervention.

  • Women, Hormones and Longevity

    What perimenopause does to metabolism, body composition, and risk, and what to do about it.

  • GLP-1s, Muscle Preservation and the Future of Metabolic Medicine

    How to use GLP-1 medications without trading fat for muscle, from a surgeon who has seen both outcomes.

  • Biomarkers, Wearables and Personalized Longevity

    Turning CGM, VO2 max, body composition, and blood panels into decisions instead of dashboards.

  • Performance, Recovery and Human Optimization

    Applying longevity medicine to athletes, executives, and anyone who wants to perform at 50 like they did at 35.

  • The Future of Medicine: From Disease Treatment to Healthspan Extension

    Why the next decade of healthcare moves upstream, and what that means for practitioners and patients.

  • The Practitioner as the Patient

    Teaching healthcare providers to put their own health first before burnout decides for them.

Ask Dr. Sweeney

I'm on a GLP-1 and losing weight fast. Why do you keep talking about muscle?

Because if we are sacrificing muscle just to be a smaller pant size, we are shortening our life. Muscle is the organ of longevity. It clears glucose, holds you upright at 80, and predicts how long you live independent of what the scale says. In my practice, GLP-1 patients train with resistance, hit a protein target, and get a body composition scan every visit so we know what they lost. The drug is a tool. The protocol around it decides the outcome.

What is the one test everyone over 40 should get that their doctor probably is not ordering?

Fasting insulin, and right behind it, an omega-3 index. A normal fasting glucose can sit on top of insulin that has been climbing for a decade. By the time glucose moves, you have lost years of runway. Insulin is the #1 biomarker of healthspan, and the longest-living people on Earth have low fasting insulin levels, so you need to know what yours is. On omega-3, nine out of ten patients who walk into my office test below 4 percent. The longevity literature target is above 8. Standard labs call 5 fine. Those two numbers tell me more about where you are headed than your typical annual physical.

You were a surgeon in the conventional healthcare model for two decades. Why leave?

Because I was tired of working in the conventional system that treats patients reactively rather than proactively. Most bariatric surgery patients that I operated on didn't need to be there in the first place. Their disease could have been treated decades before they met me. Bariatric surgery works. I believe in it. But I also believe in a proactive healthcare model. I can identify the precursors to disease long before conventional medicine makes a diagnosis. This gives us plenty of time to make changes and optimize someone's health for the long run. There is a lot of illegitimate noise in the longevity space. I am the legitimate one that cuts through the noise with real science, experience, and outcomes.

Media and podcast appearances

Television and press

Podcasts and webinars

Dr. Meredith Sweeney, longevity physician, recording a podcast interview in the studio

Speaking

  • LongevityFest (A4M), Las VegasChanging the Trajectory of Longevity: Using Continuous Glucose Monitoring as a Personalized Medicine Tool to Extend Healthspan

Work with Dr. Sweeney

Three ways to work with Dr. Sweeney. Pick the one that fits and the form below will route it to the right place.

Speaking

Keynotes, panels, and breakout sessions for medical conferences, corporate wellness programs, and consumer health events. Talks run 20 to 60 minutes and are built from her own clinical data. Available for in-person and virtual events.

Check her availability

Media

Podcast interviews, television segments, and expert commentary on longevity, metabolic health, GLP-1 medications, and women's health. She has done eight podcasts and a WAVE 3 television segment since 2025 and turns around scheduling requests within five business days.

Request an interview

Become a patient

Dr. Sweeney sees patients at Sano Longevity in Louisville, Kentucky. Every patient starts with a full metabolic baseline: a 46-marker longevity lab panel, InBody body composition scan, and PNOĒ VO2 max and metabolic rate testing.

Start at Sano Longevity

Speaking and media requests get a reply within five business days. No agency, no middleman. You hear from Meredith or her brand lead directly.

Questions producers and partners ask

Who is Dr. Meredith Sweeney?

Dr. Meredith Sweeney is a board-certified surgeon and longevity physician based in Louisville, Kentucky. She practiced bariatric surgery for 14 years and still performs general surgery part-time. She founded Sano Longevity in March 2025 and became Head of Metabolic Optimisation and Longevity at AverCare Global in January 2026. She is a Fellow of the American College of Surgeons.

What does Dr. Sweeney speak about?

Her core topics are metabolic health, longevity medicine, GLP-1 medications and muscle preservation, continuous glucose monitoring, women's health through perimenopause, and physician burnout. She was a featured speaker at LongevityFest 2025 in Las Vegas, the largest longevity conference in the United States. Request a date through the form on this page.

Is Dr. Sweeney available for podcast interviews?

Yes. She has appeared on eight podcasts since 2025, including The Clinical Tea, The Practice Pulse, The Starting Gate, and Mind Body Mother. She records remotely or in person in Louisville. Send a request through the contact form and include your show name, audience, and preferred dates.

Why did a bariatric surgeon move into longevity medicine?

Because, in her words, it is one continuum. Bariatric surgery is metabolic health at its most reactive extreme. Longevity medicine is the same problem at its most proactive. After 14 years treating the end stage, including livers so enlarged from metabolic dysfunction they took two retractors to lift, she wanted to find those patients 20 years earlier. She calls herself a fixer: start at the bottom, fix it there, and everything upstream gets better.

What is Sano Longevity?

Dr. Sweeney's longevity and metabolic health practice in Louisville, KY founded in March 2025. A sought-after, one-of-a-kind practice for patients seeking personalized longevity medicine and proactive wellness.

Does Dr. Sweeney work with corporate partners?

Yes. She works with corporate wellness programs, health technology companies, and clinical platforms. She is Head of Metabolic Optimisation and Longevity at AverCare Global, an AI-based healthcare platform launching in late 2026. Partnership inquiries go through the contact form and are answered within five business days.

Get in touch

One form for speaking, media, and partnership requests. Patient inquiries go to Sano Longevity.

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Replies within five business days. No newsletter sign-up, no sales follow-up.